As of Tuesday it seems EVE Online will be officially supported on Macs and Linux. The Linux version seems to be just improved (and official) support for running EVE with Cedega (a commercial WineX fork). At the moment only Ubuntu, openSUSE and Linspire are supported (and come with nice packages). The Mac version was developed using Cider (a modification of Cedega for Macs) and only supports Intel Macs.
The minimum hardware requirements are interesting. PRocessor and RAM are the same at 1.8GHz+ 1GB respectively. Mac users require a better graphics card than Linux users but the Linux version doesn’t support ATI graphics cards. I would guess 6 months to a year down the line when AMD have finished releasing open source versions of the ATI drivers then ATI support will exist for everything in Cedega.